2022 Men's Basketball NCAA Tournament Bracket
11/28 Bracketology Breakdown
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| Round of 64
| | Round of 32
| | Regional Semifinals | | Regional Finals | | National Semifinals | | | Final | | | National Semifinals | | Regional Finals | | Regional Semifinals | | Round of 32
| | Round of 64
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| 1 | Duke | | | | | | | | | | | | | | | | | | | | | | Gonzaga | 1 |
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| 16 | Howard / Nicholls | | | | | | | | | | | | | | | | | | | | | | Texas Southern / Campbell | 16 |
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| 8 | St. Bonaventure | | | | | | | | | | | | | | | | | | | | Indiana | 8 |
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| 9 | Texas Tech | | | | | | | | | | | | | | | | | | | |
| | Virginia Tech | 9 |
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| 5 | Tennessee | | | | | | | | | | | | | | | | | | | | | | Michigan | 5 |
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| 12 | Iona | | | | | | | | | | | | | | | | | | | | | | Belmont
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| 4 | USC | | | | | | | | | | | | | | | | | | | | Alabama | 4 |
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| 13 | South Dakota State | | | | | | | | | | | | | | | | | | | | | | Buffalo | 13 |
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| 6 | Memphis | | | | | | | | | | | | | | | |
| | Florida State | 6 |
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| 11 | Iowa | | | | | | | | | | | | | | | | | | | | | | Wichita State / Marquette | 11 |
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| 3 | Arkansas | | | | | | | | | | | | | | | | | | | | Kansas | 3 |
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| 14 | Georgia State | | | | | | | | | | | | | | | | | | | | | | Colgate | 14 |
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| 7 | Seton Hall | | | | | | | | | | | | | | | | | | | | | | LSU | 7 |
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| 10 | Maryland | | | | | | | | | | |
| | | | | | | | | | | St. Mary's | 10 |
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| 2 | Texas | | | | | | | | | | | | | | | | | | | | UCLA | 2 |
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| 15 | Chattanooga | | | | | | | | | | | | | | | | | | | | | | Liberty | 15 |
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| 1 | Baylor | | | | | | | | | | | | | | | | | | | | | | Purdue | 1 |
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| 16 | Hofstra | | | | | | | | | | | | | | | | | | | | | | Wagner | 16 |
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| 8 | North Carolina | | | | | | | | | | | | | | | | | | | | Xavier | 8 |
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| 9 | Colorado State | | | | | | | | | | | | | | | | | | | | | | Louisville | 9 |
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| 5 | Ohio State | | | | | | | | | | | | | | | | | | | | | | Auburn | 5 |
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| 12 | Utah State / Oregon | | | | | | | | | | | | | | | | | | | | | | UAB | 12 |
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| 4 | Florida | | | | | | | | | | | | | | | | | | | | BYU | 4 |
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| 13 | Vermont | | | | | | | | | | | | | | | | | | | | | | UC Santa Barbara | 13 |
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| 6 | Michigan State | | | | | | | | | | | | | | | |
| | Connecticut | 6 |
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| 11 | West Virginia | | | | | | | | | | | | | | | | | | | | | | San Diego State | 11 |
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| 3 | Houston | | | | | | | | | | | | | | | | | | | | Arizona | 3 |
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| 14 | New Mexico State | | | | | | | | | | | | | | | | | | | | | | Weber State | 14 |
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| 7 | Wisconsin | | | | | | | | | | | | | | | | | | | |
| | Illinois | 7 |
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| 10 | Iowa State | | | | | | | | | | | | | | | | | | | |
| | Loyola Chicago | 10 |
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| 2 | Villanova | | | | | | | | | | | | | | | | | | | | Kentucky | 2 |
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| 15 | Oakland | | | | | | | | | | | | | | | | | | | | | | Yale | 15 |
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